Czech Innovation Against Alzheimer’s: H2 Global Group Enters a Key Growth Phase

Czech Innovation Against Alzheimer’s: H2 Global Group Enters a Key Growth Phase

H2 Global Group, together with its subsidiary H2 Medical Technologies, has entered a decisive growth stage following strong recognition at LSI Europe 2025 in London. The group presented its breakthrough approach to preventing and treating neurodegenerative diseases, including Alzheimer’s, confirming its position among global leaders in the MedTech and HealthTech sectors.

At the core of this innovation is a prototype medical device for controlled hydrogen therapy, developed by H2 Medical Technologies. The device is designed for patients with mild cognitive impairment, a condition that often precedes Alzheimer’s. Non-invasive and suitable for both clinical and home use, it is based on a patented method pioneered by a Japanese team led by Professor Shigeo Ohta, co-owner of H2 Global Group. Research indicates that molecular hydrogen can protect brain cells, slow inflammation, and support neuronal metabolism and connectivity.

“Hydrogen is the smallest molecule in the universe, yet it can protect our most valuable assets – memory and independence,” explains Prof. Ohta.

Group founder David Maršálek, who has been developing hydrogen technologies since 2011, adds: “Our mission is to launch the world’s first hydrogen-based medical device for Alzheimer’s prevention and therapy support. With strong scientific evidence, patent protection, and an experienced team, we are positioned to succeed.”

Between 2021 and 2025, H2 Global Group raised over $18M in Seed funding, built a network of 20,000 end-customers and 50+ B2B partners, and exceeded revenues of circa $7.4M. Current transactions value the group at circa $77M.

Now entering Series A, the group plans to raise $25–30 million to fund global expansion into Europe, the U.S., the Middle East, and Africa, complete clinical trials, and secure EU and FDA registrations. Revenue projections forecast growth to nearly $48M by 2029.

The portfolio extends beyond the medical device. H2 Medical Technologies supplies hydrogen generators and therapeutic systems to spas, sports clubs, physiotherapy practices or dental clinics. Its solutions are also approved for veterinary use. In parallel, H2 Pharm develops consumer products such as H2 Premium Water®, H2 Brain®, H2 Forte®, and H2 Dent Care®, which are commercially successful and distributed via e-commerce and a B2B network.

“Such opportunities are rare,” concludes Maršálek. “When future textbooks are written, our investors will say: I was there. Hydrogen is not only energy source but a molecule of lifeconnecting the world. Invest in Hydrogen!”

Source: ap.news.com

Czech MedTech Startup H2 Medical Technologies Unveils World’s First Patented Hydrogen-Based Therapy with the Potential to Target Alzheimer’s Disease

Czech MedTech Startup H2 Medical Technologies Unveils World’s First Patented Hydrogen-Based Therapy with the Potential to Target Alzheimer’s Disease

H2 Medical Technologies, part of the H2 Global Group, has developed the world’s first functional hydrogen-based therapy medical device prototype for clinical trials — aimed at both preventing and treating Alzheimer’s disease.

Today, more than 6.5 million Americans and 50 million people worldwide are living with Alzheimer’s and other forms of dementia. According to the World Health Organization, this number could triple by 2050, placing an immense burden on families and healthcare systems. Despite decades of research, no effective solution has been found — until now.

“This is not another experiment — it is the first technology in the world with the potential to prevent Alzheimer’s disease before it even starts, while supporting those already affected,” says David Marsalek, founder and CEO of H2 Global Group. The company believes its effectiveness will be further confirmed in an upcoming new clinical trial. “Our mission is clear: to turn decades of research into real hope for millions of families around the world. We are part of a strong vision of a society where hydrogen is the molecule of life that connects the world.”

From the Lab to the Global Stage

H2 Global Group will present this breakthrough at LSI Europe 2025 in London, one of the world’s most prestigious MedTech and HealthTech conferences. The project builds on 30+ years of research and patents developed with Professor Shigeo Ohta, a global leader in molecular hydrogen science and co-founder of H2 Global Group.

More Than Medicine: A New Era of Brain Health

While the immediate focus is Alzheimer’s, potential applications extend to neurological disorders, brain regeneration, and healthy aging.

Alongside its medical device, H2 Global Group has launched consumer products such as H2 Premium Water® and H2 Brain®, a world-first two-phase dietary supplement that stimulates molecular hydrogen production through the gut microbiome. The company is also the only certified global manufacturer authorized to use hydrogen-based medical devices in veterinary medicine.

Today, its hydrogen-based solutions are already being adopted by wellness centers, rehabilitation clinics, dental practices, and elite sports organizations across Europe — underscoring the broad potential of the technology.

An Opportunity for Visionary Investors

Until now, the project has been funded primarily by Czech investors. H2 Global Group is now opening the door to U.S. and global partners at a critical growth stage, with EU registration underway and FDA approval next on the horizon — unlocking the world’s largest healthcare market.

The global Alzheimer’s therapeutics market is projected to exceed $20 billion by 2030, with dementia-related costs already surpassing $1 trillion annually. Positioned as the only functional hydrogen-based therapy of its kind, H2 Global Group offers investors a rare first-mover advantage in one of the most urgent and lucrative markets of our time.

Scientists claim: A healthy mouth equals a healthy body and brain

Scientists claim: A healthy mouth equals a healthy body and brain

Oral Health: A Gateway to Whole-Body Wellbeing

Oral health is not merely a matter of a bright smile and fresh breath. A growing body of scientific evidence suggests that bacteria residing in the mouth may have far-reaching consequences for overall health, potentially contributing to serious conditions such as heart disease, Alzheimer’s disease, and even cancer. These findings underline the importance of dental care and the prevention of pathogenic bacteria spreading into the bloodstream and beyond.

What Is the Oral Microbiome?
The oral microbiome is a complex community of microorganisms inhabiting the mouth. This includes bacteria, fungi, viruses, and other microbes that together form a unique ecosystem. While many of these organisms play a beneficial role in maintaining oral health, others can lead to tooth decay, gum disease, and other disorders if they multiply excessively. Maintaining balance within this microbiome is essential—disturbances caused by poor hygiene or an unhealthy diet can lead to inflammation and allow harmful bacteria to enter the bloodstream, potentially affecting the entire body. Supporting a healthy microbiome through proper oral hygiene and balanced nutrition is key to preventing numerous health issues.

From Mouth to Body: Cancer and Other Illnesses
Poor oral hygiene is far more than a cosmetic concern. A study published in the UEG Journal linked poor oral health to an increased risk of liver cancer. Pathogenic oral bacteria can enter the bloodstream and migrate to the liver, potentially causing damage and increasing cancer risk. Likewise, bacteria associated with gum disease have been shown to play a role in the development of cardiovascular disease and diabetes.

How Can You Protect Your Health?
Prevention is essential. Here are several ways to reduce the risk of harmful bacteria spreading from the mouth:

  • Daily dental care: Brushing twice a day, flossing, and using interdental brushes should form part of your everyday routine. Proper cleaning prevents bacterial overgrowth and helps guard against tooth decay and gum disease.

  • Regular dental check-ups and professional cleanings: Early detection and treatment of tooth decay and gum inflammation can help prevent bacterial spread.

  • Supporting a healthy microbiome: A balanced diet rich in vitamins and minerals, reduced sugar intake, and targeted supplements—such as molecular hydrogen—can support gum health and reduce inflammation.

Molecular Hydrogen and Oral Health
One emerging option for promoting oral health is the use of molecular hydrogen, available in products such as hydrogen-rich water or H2 Dent Care. Molecular hydrogen offers antioxidant and anti-inflammatory benefits that may help to reduce oxidative stress in the mouth and support gum regeneration. Regular use can aid in prevention as well as complement treatment of gum disease. Start your oral care routine each morning by rinsing with hydrogen water—before breakfast!

Oral health has a profound impact on the health of the entire body. Caring for your teeth and preventing the spread of bacteria from the mouth are not only vital for avoiding tooth decay but also crucial in protecting the brain, heart, and other essential organs. As science increasingly shows, a healthy mouth is the foundation of a healthy life.

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