Czech Innovation Against Alzheimer’s: H2 Global Group Enters a Key Growth Phase

Czech Innovation Against Alzheimer’s: H2 Global Group Enters a Key Growth Phase

H2 Global Group, together with its subsidiary H2 Medical Technologies, has entered a decisive growth stage following strong recognition at LSI Europe 2025 in London. The group presented its breakthrough approach to preventing and treating neurodegenerative diseases, including Alzheimer’s, confirming its position among global leaders in the MedTech and HealthTech sectors.

At the core of this innovation is a prototype medical device for controlled hydrogen therapy, developed by H2 Medical Technologies. The device is designed for patients with mild cognitive impairment, a condition that often precedes Alzheimer’s. Non-invasive and suitable for both clinical and home use, it is based on a patented method pioneered by a Japanese team led by Professor Shigeo Ohta, co-owner of H2 Global Group. Research indicates that molecular hydrogen can protect brain cells, slow inflammation, and support neuronal metabolism and connectivity.

“Hydrogen is the smallest molecule in the universe, yet it can protect our most valuable assets – memory and independence,” explains Prof. Ohta.

Group founder David Maršálek, who has been developing hydrogen technologies since 2011, adds: “Our mission is to launch the world’s first hydrogen-based medical device for Alzheimer’s prevention and therapy support. With strong scientific evidence, patent protection, and an experienced team, we are positioned to succeed.”

Between 2021 and 2025, H2 Global Group raised over $18M in Seed funding, built a network of 20,000 end-customers and 50+ B2B partners, and exceeded revenues of circa $7.4M. Current transactions value the group at circa $77M.

Now entering Series A, the group plans to raise $25–30 million to fund global expansion into Europe, the U.S., the Middle East, and Africa, complete clinical trials, and secure EU and FDA registrations. Revenue projections forecast growth to nearly $48M by 2029.

The portfolio extends beyond the medical device. H2 Medical Technologies supplies hydrogen generators and therapeutic systems to spas, sports clubs, physiotherapy practices or dental clinics. Its solutions are also approved for veterinary use. In parallel, H2 Pharm develops consumer products such as H2 Premium Water®, H2 Brain®, H2 Forte®, and H2 Dent Care®, which are commercially successful and distributed via e-commerce and a B2B network.

“Such opportunities are rare,” concludes Maršálek. “When future textbooks are written, our investors will say: I was there. Hydrogen is not only energy source but a molecule of lifeconnecting the world. Invest in Hydrogen!”

Source: ap.news.com

Czech MedTech Startup H2 Medical Technologies Unveils World’s First Patented Hydrogen-Based Therapy with the Potential to Target Alzheimer’s Disease

Czech MedTech Startup H2 Medical Technologies Unveils World’s First Patented Hydrogen-Based Therapy with the Potential to Target Alzheimer’s Disease

H2 Medical Technologies, part of the H2 Global Group, has developed the world’s first functional hydrogen-based therapy medical device prototype for clinical trials — aimed at both preventing and treating Alzheimer’s disease.

Today, more than 6.5 million Americans and 50 million people worldwide are living with Alzheimer’s and other forms of dementia. According to the World Health Organization, this number could triple by 2050, placing an immense burden on families and healthcare systems. Despite decades of research, no effective solution has been found — until now.

“This is not another experiment — it is the first technology in the world with the potential to prevent Alzheimer’s disease before it even starts, while supporting those already affected,” says David Marsalek, founder and CEO of H2 Global Group. The company believes its effectiveness will be further confirmed in an upcoming new clinical trial. “Our mission is clear: to turn decades of research into real hope for millions of families around the world. We are part of a strong vision of a society where hydrogen is the molecule of life that connects the world.”

From the Lab to the Global Stage

H2 Global Group will present this breakthrough at LSI Europe 2025 in London, one of the world’s most prestigious MedTech and HealthTech conferences. The project builds on 30+ years of research and patents developed with Professor Shigeo Ohta, a global leader in molecular hydrogen science and co-founder of H2 Global Group.

More Than Medicine: A New Era of Brain Health

While the immediate focus is Alzheimer’s, potential applications extend to neurological disorders, brain regeneration, and healthy aging.

Alongside its medical device, H2 Global Group has launched consumer products such as H2 Premium Water® and H2 Brain®, a world-first two-phase dietary supplement that stimulates molecular hydrogen production through the gut microbiome. The company is also the only certified global manufacturer authorized to use hydrogen-based medical devices in veterinary medicine.

Today, its hydrogen-based solutions are already being adopted by wellness centers, rehabilitation clinics, dental practices, and elite sports organizations across Europe — underscoring the broad potential of the technology.

An Opportunity for Visionary Investors

Until now, the project has been funded primarily by Czech investors. H2 Global Group is now opening the door to U.S. and global partners at a critical growth stage, with EU registration underway and FDA approval next on the horizon — unlocking the world’s largest healthcare market.

The global Alzheimer’s therapeutics market is projected to exceed $20 billion by 2030, with dementia-related costs already surpassing $1 trillion annually. Positioned as the only functional hydrogen-based therapy of its kind, H2 Global Group offers investors a rare first-mover advantage in one of the most urgent and lucrative markets of our time.

Janské lázně SPA and hydrogen therapy

Janské lázně SPA and hydrogen therapy

Janské Lázně has long held a reputation as one of the premier spa destinations in the Czech Republic. Nestled in the Krkonoše Mountains, it also serves as an ideal starting point for sports and recreational activities. In addition to its renowned electroacupuncture treatments—an innovative technique that combines traditional acupuncture with advances in physical medicine and offers hope especially to those with spinal cord injuries—the spa has also embraced the increasingly popular molecular hydrogen therapy.

Visitors to Janské Lázně can enjoy a wide array of experiences, from the spa’s Aquacentre featuring a pool, whirlpools, and saunas, to the famous children’s treatment facility Vesna, as well as stylish hotels and cafés hosting concerts, exhibitions, talks, dances, and markets.

Often referred to affectionately as “Jánky” by returning guests, this spa jewel of the Krkonoše specialises in a wide range of therapeutic services. It is the perfect destination for anyone seeking relief from conditions such as musculoskeletal disorders, post-injury or post-surgery recovery, neuromuscular and neurological conditions, asthma, respiratory issues, paralysis, multiple sclerosis, or oncological diagnoses.

Vesna: A Beloved Haven for Children’s Healing
The Vesna children’s spa facility at Janské Lázně has gained global recognition for its successful treatment of children affected by polio. The local spring water, discovered in 1934, shares similar therapeutic properties with the famous Warm Springs in Georgia, USA—a fact noted by Dr Viktor Sellner, who introduced treatment here in 1935. Vesna’s unique mountain location provides a serene atmosphere ideal for rehabilitation.

A particularly popular offering is the self-funded hydrogen therapy stay using H2 Medical devices. Parents of children suffering from respiratory difficulties often choose this option, and many decide to purchase a molecular hydrogen generator for home use following their visit.

Molecular hydrogen has anti-inflammatory and regenerative properties, combats the effects of viral infections, and is the most powerful antioxidant known. Hydrogen-enriched water boosts energy, reduces fatigue, and supports the body in fighting lifestyle-related diseases. The treatment programme includes hydrogen inhalation, full-body bubble baths infused with molecular hydrogen, hydrogen water therapy, and more.

Fast-Acting Hydrogen Therapy
Since January 2023, children undergoing treatment at Janské Lázně have had access to molecular hydrogen therapy using devices from H2 Medical Technologies. “From our experience, parents especially appreciate the reduced frequency and severity of recurrent respiratory infections in their children,” says Dr Pavla Fišerová, a physician on the spa’s rehabilitation team. “Mothers with children in large school groups often report noticeable improvements even during their stay, compared to previous visits. We’ve also seen positive effects on post-traumatic healing.”

Monika Stránská, mother of seven-year-old Magdalénka—who visits Janské Lázně for neurorehabilitation—was delighted by the therapy’s effects. “She inhaled molecular hydrogen twice a day and seemed so energetic. She hardly needed a nap after lunch and appeared happier overall. We’ve tried many intensive programmes elsewhere, but nothing had the same effect.”

A Breakthrough in Paralysis Treatment
Janské Lázně is at the forefront of an innovative treatment approach for patients with mobility impairments: electroacupuncture. This therapy, which combines traditional acupuncture with modern electrostimulation, offers new hope for those with spinal cord injuries and other serious health conditions. It has already brought life-changing improvements to over 700 patients.

By combining acupuncture needles with electrical stimulation, the treatment helps restore the function of damaged nerve pathways—offering significant improvement and a renewed quality of life.

Tip: Fancy a Long Weekend in the Krkonoše?
Relax in the spa’s wellness zone, indulge in delicious desserts at Kolonáda Café, or enjoy a trip to the cinema. Discover a true oasis of calm in the unique climate of Janské Lázně—now with 20% off all wellness stays.

Clients of Teplice nad Bečvou Spa enjoy hydrogen therapy

Clients of Teplice nad Bečvou Spa enjoy hydrogen therapy

Teplice nad Bečvou Spa: A Pioneer in Hydrogen Therapy

Teplice nad Bečvou Spa has become one of the leading providers of hydrogen therapy in the Czech Republic. Since 2020, this innovative treatment has been gaining popularity among clients who value its beneficial effects on overall health and immunity. “It appears that hydrogen supports the effectiveness of traditional spa therapy,” says Chief Physician Gabriela Hanslianová.

The spa offers hydrogen therapy to self-paying clients in various forms, including inhalation, drinking cures, full-body or partial baths enriched with molecular hydrogen, and specialised massages. The equipment and supplementary products are supplied by H2 Global Group, an Ostrava-based company specialising in the production and distribution of hydrogen-based technologies.

“Molecular hydrogen has proven to be a powerful complement to our traditional spa treatments,” explains Dr Hanslianová. “We use it to enhance the effects of hydrotherapy—both in baths and massages—but inhalation remains the most popular application among our clients.”

Dr Hanslianová and her team were among the first to introduce hydrogen therapy within a state-run spa facility in the Czech Republic. “I’ve been interested in the effects of hydrogen for a long time, but it wasn’t until 2020 that we had the chance to explore its potential in spa medicine more closely, during a visit to Dr Peták’s Sanatorium in Mariánské Lázně. Since then, we’ve been using it in Teplice nad Bečvou. The mysteries of hydrogen are still being uncovered, but it seems to enhance the effects of conventional spa treatments,” she adds.

Celebrating the Spa Season with Hydrogen in the Spotlight
The subsidiary company H2 World Health & Beauty, part of H2 Global Group, will join Teplice nad Bečvou Spa for the Opening of the Spa Season and Spa Run, taking place on Saturday 18 May at the spa complex.

This popular event will offer clients a chance to explore the benefits of hydrogen therapy first-hand, try H2 PREMIUM Hydrogen Water and other hydrogen-based supplements, and take part in a 5, 12, or 21 km run. A lively accompanying programme will round out the day, with the highlight being a performance by Jiří Pavlica and his ensemble Hradišťan.

Gabriela Hanslianová M.D.: Hydrogen increases the effects of our spa

Gabriela Hanslianová M.D.: Hydrogen increases the effects of our spa

MUDr. Gabriela Hanslianová works as the head of spa and rehabilitation care at the Lázně Teplice nad Bečvou. The history of this spa dates back to 1553. The spa is especially famous for its excellent cardiac rehabilitation, especially in the field of prevention of heart and stroke. Thanks to the cooperation with H2 Global Group, the Lázně Teplice nad Bečvou now also offers its guests treatments enriched with Molecular Hydrogen®.
We asked the headmistress for an interview.

Mrs. Chief Medical Officer, what is the current awareness of the Czech public about spa treatments with molecular hydrogen? And what is the feedback from spa guests who have undergone these treatments with you?

“Many of our clients are experiencing molecular hydrogen for the first time directly at our spa, either on the basis of a doctor’s recommendation, or it is the clients themselves who share their impressions of the treatments. Recently, I have seen the gradual introduction of hydrogen in other spas, I know that it is used in Janské Lázně or Slatinice.

At first, the response is somewhat embarrassing, as hydrogen is a tasteless and odourless gas, so you hardly notice anything during the treatment. Generally speaking, however, the more exhausted the body is, the faster you start to notice the effects of hydrogen on yourself.”

How long has your spa been using molecular hydrogen and in what form?

“We have been using hydrogen for about 3 years in the form of inhalations, most often with patients after a covid, and you can also ‘taste’ non-traditional forms of hydrogen use – full-body baths, but also partial – hand and foot baths, you can also try massages with hydrogen.

According to our experience, hydrogen enhances the effect of traditional spa treatments. From an empirical point of view, a spa treatment should last 3-4 weeks, but in today’s hectic times few people can afford it, so we use it mainly for self-payers whose stays are significantly shorter.”

 

An interesting hydrogen scientific study is currently underway in cooperation with Associate Professor Michal Botek from the Faculty of Physical Culture of Palacký University in Olomouc. What is the aim of this study and are any results already known?

“In this study, we are investigating the effect of four weeks of molecular hydrogen inhalation on the change in the functional state of the organism in spa patients suffering from inflammatory rheumatic health problems. This is a double-blind study, meaning that neither the patients, nor the referring physicians, nor even the researchers evaluating the study know until the last minute whether the patient is inhaling hydrogen or air. I am very curious about the outcome of this study, as it already looks very interesting after ‘examining’ a small number of participants. I think that this gas will surprise us in many ways. But we cannot predict the outcome of the study.”

What types of stays and treatments involving molecular hydrogen can people choose from at your spa in 2023?

“For this year we have decided to simplify the choice of stays for our clients. You can taste the most hydrogen in a week-long stay called Molecularia, in which you can recharge during one week with a full-body whirlpool, an upper or lower limb whirlpool, you can also try a molecular hydrogen back and neck massage as well as a hand massage, paraffin enriched with molecular hydrogen and of course daily hydrogen inhalations. You can certainly add all the treatments listed above to any stay.”

How do you, as a physician, see the future of molecular hydrogen in the Czech health, spa and wellness sector in the next ten years?

“Even more domestic studies will be needed for molecular hydrogen to make its way into classical Western medicine, and perhaps the spa industry is the right way to help this happen. There are several studies on the miracle waters of Lourdes and many of them agree that it is the increased amount of molecular hydrogen that is behind their fame. In our experience, this element also enhances the effects of our time-honoured treatments, so in these hectic times when we want to speed things up, I believe it will find its place.”

Can we please conclude by asking: Do you use molecular hydrogen-based products and treatments yourself?

“Yes, I use H2 Immunity DRINK, which for me has an effect similar to some of the touted energy drinks.”

 

Pictures: Lázně Teplice nad Bečvou a.s.

H2 Global Group
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